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CIFALDI L.-LO MONACO E.-FORLONI M.-GIORDA E.-LORENZI S.-PETRINI S.-
TREMANTE E.-PENDE D.-LOCATELLI F.-GIACOMINI P.-FRUCI D.
Natural killer cells efficiently reject lymphoma silenced for the
endoplasmic reticulum aminopeptidase associated with antigen
processing.
Cancer Res. 71(5):1597/1606, 2011
PubMed Abstract
MEAZZA R.-AZZARONE B.-ORENGO A.M.-FERRINI S.
Role of common gamma chain cytokines in NK cell development and
function: perspectives for immunotherapy.
J. Biomed. Biotechnol. 2011:861920;1/861920;16, 2011
PubMed Abstract
MORETTA L.-LOCATELLI F.-PENDE D.-SIVORI S.-FALCO M.-BOTTINO C.-
MINGARI M.C.-MORETTA A.
Human NK receptors: from the molecules to the therapy of high risk
leukemias.
FEBS Lett. 585:1563/1567, 2011
PubMed Abstract
SIENI E.-CETICA V.-SANTORO A.-BEUTEL K.-MASTRODICASA E.-MEETHS M.-
CIAMBOTTI B.-BRUGNOLO F.-ZUR STADT U.-PENDE D.-MORETTA L.-
GRIFFITHS G.-HENTER J.-JANKA G.-ARICO' M.
Genotype phenotype study of familial haemophagocytic
lymphohistiocytosis type 3.
J. Med. Genet. 48:343/352, 2011
PubMed Abstract
STINCHCOMBE J.-SALIO M.-CERUNDOLO V.-PENDE D.-ARICO M.-GRIFFITHS G.
Centriole polarisation to the immunological synapse directs
secretion from cytolytic cells of both the innate and adaptive
immune systems.
BMC Biol. 9:45;1/45;8, 2011
PubMed Abstract
CETICA V.-PENDE D.-GRIFFITHS G.-ARICO' M.
Molecular basis of familial hemophagocytic lymphohistiocytosis.
Haematologica 95(4):538/541, 2010
PubMed Abstract
CETICA V.-SANTORO A.-GILMOUR K.-SIENI E.-BEUTEL K.-PENDE D.-
MARCENARO S.-KOCH F.-GRIEVE S.-WHEELER R.-ZHAO F.-ZUR STADT U.-
GRIFFITHS G.-ARICO' M.
STXBP2 mutations in children with familial haemophagocytic
lymphohistiocytosis type 5.
J. Med. Genet. 47:595/600, 2010
PubMed Abstract
ELHMOUZI YOUNES J.-BOYSEN P.-PENDE D.-STORSET A.-LE VERN Y.-
LAURENT F.-DROUET F.
Ovine CD16+/CD14- blood lymphocytes present all the major
characteristics of natural killer cells.
Vet. Res. 41:4;1/4;12, 2010
PubMed Abstract
FALCO M.-ROMEO E.-MARCENARO S.-MARTINI S.-VITALE M.-BOTTINO C.-
MINGARI M.C.-MORETTA L.-MORETTA A.-PENDE D.
Combined genotypic and phenotypic killer cell Ig like receptor
analyses reveal KIR2DL3 alleles displaying unexpected monoclonal
antibody reactivity: identification of the amino acid residues
critical for staining.
J. Immunol. 185:433/441, 2010
PubMed Abstract
MAGRI G.-MUNTASELL A.-ROMO N.-SAEZ BORDERIAS A.-PENDE D.-GERAGHTY
D.-HENGEL H.-ANGULO A.-MORETTA A.-LOPEZ BOTET M.
NKp46 and DNAM/1 NK cell receptors drive the response to human
cytomegalovirus infected myeloid dendritic cells overcoming viral
immune evasion strategies.
Blood 117(3):848/856, 2011 - Epub Oct 28, 2010
PubMed Abstract
MORETTA L.-LOCATELLI F.-PENDE D.-MARCENARO E.-MINGARI M.C.-MORETTA A.
Killer Ig like receptor mediated control of natural killer cell
alloreactivity in haploidentical hematopoietic stem cell
transplantation.
Blood 117(3):764/771, 2011 - Epub Oct 1, 2010
PubMed Abstract
MUNTASELL A.-MAGRI G.-PENDE D.-ANGULO A.-LOPEZ BOTET M.
Inhibition of NKG2D expression in NK cells by cytokines secreted
in response to human cytomegalovirus infection.
Blood 115(25):5170/5179, 2010
PubMed Abstract
BALSAMO M.-ZAMBELLO R.-TERAMO A.-PEDRAZZI M.-SPARATORE B.-
SCORDAMAGLIA F.-PENDE D.-MINGARI M.C.-MORETTA L.-MORETTA A.-
SEMENZATO G.-VITALE M.
Analysis of NK cell/DC interaction in NK type lymphoproliferative
disease of granular lymphocytes (LDGL): role of DNAM/1 and NKp30.
Exp. Hematol. 37:1167/1175, 2009
PubMed Abstract
CARREGA P.-PEZZINO G.-QUEIROLO P.-BONACCORSI I.-FALCO M.-VITA G.-
PENDE D.-MISEFARI A.-MORETTA A.-MINGARI M.C.-MORETTA L.-FERLAZZO G.
Susceptibility of human melanoma cells to autologous natural
killer (NK) cell killing: HLA related effector mechanisms and role
of unlicensed NK cells.
PLoS One 4:e8132;1/e8132;10, 2009
PubMed Abstract
LAKSHMIKANTH T.-BURKE S.-ALI T.-KIMPFLER S.-URSINI F.-RUGGERI L.-
CAPANNI M.-UMANSKY V.-PASCHEN A.-SUCKER A.-PENDE D.-GROH V.-
BIASSONI R.-HOGLUND P.-KATO M.-SHIBUYA K.-SCHADENDORF D.-ANICHINI
A.-FERRONE S.-VELARDI A.-KARRE K.-SHIBUYA A.-CARBONE E.-COLUCCI F.
NCRs and DNAM/1 mediate NK cell recognition and lysis of human and
mouse melanoma cell lines in vitro and in vivo.
J. Clin. Invest. 119:1251/1263, 2009
PubMed Abstract
LOCATELLI F.-PENDE D.-MACCARIO R.-MINGARI M.C.-MORETTA A.-MORETTA L.
Haploidentical hemopoietic stem cell transplantation for the
treatment of high risk leukemias: how NK cells make the difference.
Clin. Immunol. 133:171/178, 2009
PubMed Abstract
MARCENARO E.-CANTONI C.-PESCE S.-PRATO C.-PENDE D.-AGAUGUE' S.-
MORETTA L.-MORETTA A.
Uptake of CCR7 and acquisition of migratory properties by human
KIR+ NK cells interacting with monocyte derived DC or EBV cell
lines: regulation by KIR/HLA class I interaction.
Blood 114:4108/4116, 2009
PubMed Abstract
MORETTA A.-PENDE D.-LOCATELLI F.-MORETTA L.
Activating and inhibitory killer immunoglobulin like receptors
(KIR) in haploidentical haemopoietic stem cell transplantation to
cure high risk leukaemias.
Clin. Exp. Immunol. 157:325/331, 2009
PubMed Abstract
MORETTA L.-LOCATELLI F.-PENDE D.-MINGARI M.C.-MORETTA A.
Natural killer alloeffector responses in haploidentical
hemopoietic stem cell transplantation to treat high risk leukemias.
Tissue Antigens 75:103/109, 2010 - Epub Dec 9, 2009
PubMed Abstract
FOGLI M.-MAVILIO D.-BRUNETTA E.-VARCHETTA S.-ATA K.-ROBY G.-KOVACS
C.-FOLLMANN D.-PENDE D.-WARD J.-BARKER E.-MARCENARO E.-MORETTA A.-
FAUCI A.
Lysis of endogenously infected CD4+ T cell blasts by rIL/2
activated autologous natural killer cells from HIV infected
viremic individuals.
PLoS Pathog. 4:7;1/7;13, 2008
PubMed Abstract
PENDE D.-MARCENARO S.-FALCO M.-MARTINI S.-BERNARDO M.-MONTAGNA D.-
ROMEO E.-COGNET C.-MARTINETTI M.-MACCARIO R.-MINGARI M.C.-VIVIER
E.-MORETTA L.-LOCATELLI F.-MORETTA A.
Anti leukemia activity of alloreactive NK cells in KIR ligand
mismatched haploidentical HSCT for pediatric patients: evaluation
of the functional role of activating KIR and redefinition of
inhibitory KIR specificity.
Blood 113:3119/3129, 2009 - Epub Oct 22, 2008
PubMed Abstract
SANTORO A.-CANNELLA S.-TRIZZINO A.-BRUNO G.-DE FUSCO C.-
NOTARANGELO L.-PENDE D.-GRIFFITHS G.-ARICO' M.
Mutations affecting mRNA splicing are the most common molecular
defect in patients with familial hemophagocytic
lymphohistiocytosis type 3.
Haematologica 93:1086/1090, 2008
PubMed Abstract
SCHMUDDE M.-BRAUN A.-PENDE D.-SONNEMANN J.-KLIER U.-BECK J.-
MORETTA L.-BROKER B.
Histone deacetylase inhibitors sensitize tumour cells for
cytotoxic effects of natural killer cells.
Cancer Lett. 272:110/121, 2008
PubMed Abstract
BOYSEN P.-GUNNES G.-PENDE D.-VALHEIM M.-STORSET A.
Natural killer cells in lymph nodes of healthy calves express CD16 and
show both cytotoxic and cytokine producing properties.
Dev. Comp. Immunol. 32:773/783, 2008 - Epub Dec 18, 2007
PubMed Abstract
ENDT J.-McCANN F.-ALMEIDA C.-URLAUB D.-LEUNG R.-PENDE D.-DAVIS D.-WATZL C.
Inhibitory receptor signals suppress ligation induced recruitment of NKG2D to GM1/Rich membrane domains at the human NK cell immune synapse.
J. Immunol. 178:5606/5611, 2007
PubMed Abstract
MACCALLI C.-NONAKA D.-PIRIS A.-PENDE D.-RIVOLTINI L.-CASTELLI C.-PARMIANI G.
NKG2D mediated antitumor activity by tumor infiltrating lymphocytes and
antigen specific T cell clones isolated from melanoma patients.
Clin. Cancer Res. 13:7459/7468, 2007
PubMed Abstract
NEDVETZKI S.-SOWINSKI S.-EAGLE R.-HARRIS J.-VELY F.-PENDE D.-TROWSDALE J.-VIVIER E.-GORDON S.-DAVIS D.
Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses.
Blood 109:3776/3785, 2007
PubMed Abstract
RUGGERI L.-MANCUSI A.-CAPANNI M.-URBANI E.-CAROTTI A.-ALOISI T.-STERN M.-PENDE D.-PERRUCCIO K.-BURCHIELLI E.-TOPINI F.-BIANCHI E.-
AVERSA F.-MARTELLI M.-VELARDI A.
Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid
leukemia: challenging its predictive value.
Blood 110:433/440, 2007
PubMed Abstract
TRIZZINO A.-ZUR STADT U.-UEDA I.-RISMA K.-JANKA G.-ISHII E.-BEUTEL K.-SUMEGI
J.-CANNELLA S.-PENDE D.-MIAN A.-HENTER J.-GRIFFITHS G.-SANTORO A.-FILIPOVICH A.-ARICO'
M.
Genotype phenotype study of familial hemophagocytic lymphohistiocytosis
due to perforin mutations.
J. Med. Genet. 45:15/21, 2008 - Epub Sep 14, 2007
PubMed Abstract
LIONELLO I.-MANGIA P.-GATTINONI L.-PENDE D.-CIPPONE A.-SENSI M.-
RIGATTI P.-TRAVERSARI C.
CD8+ T lymphocytes isolated from renal cancer patients recognize
tumour cells through an HLA and TCR/CD3 independent pathway.
Cancer Immunol. Immunother. 56:1065/1076, 2007 - Epub Dec 29, 2006
PubMed Abstract
MARCENARO S.-GALLO F.-MARTINI S.-SANTORO A.-GRIFFITHS G.-ARICO' M.-MORETTA L.-PENDE D.
Analysis of natural killer cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface
expression heralds Munc13/4 defect and discriminates between genetic subtypes of the disease.
Blood 108:2316/2323, 2006
PubMed Abstract
MAVILIO D.-LOMBARDO G.-KINTER A.-FOGLI M.-LA SALA A.-ORTOLANO S.-FARSCHI A.-FOLLMANN D.-GREGG R.-KOVACS C.-MARCENARO E.-PENDE D.-MORETTA A.-FAUCI A.
Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV/1 infection.
J. Exp. Med. 203:2339/2350, 2006
PubMed Abstract
MORETTA L.-BOTTINO C.-PENDE D.-CASTRICONI R.-MINGARI M.C.-MORETTA A.
Surface NK receptors and their ligands on tumor cells.
Semin. Immunol. 18:151/158, 2006
PubMed Abstract
MORETTA L.-FERLAZZO G.-BOTTINO C.-VITALE M.-PENDE D.-MINGARI M.C.-MORETTA A.
Effector and regulatory events during natural killer dendritic cell interactions.
Immunol. Rev. 214:219/228, 2006
PubMed Abstract
PENDE D.-CASTRICONI R.-ROMAGNANI P.-SPAGGIARI G.-MARCENARO S.-DONDERO A.-LAZZERI E.-LASAGNI L.-MARTINI S.-RIVERA P.-CAPOBIANCO A.-
MORETTA L.-MORETTA A.-BOTTINO C.
Expression of the DNAM/1 ligands, nectin/2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for
natural killer dendritic cell interaction.
Blood 107:2030/2036, 2006
PubMed Abstract
SAEZ BORDERIAS A.-GUMA M.-ANGULO A.-BELLOSILLO B.-PENDE D.-LOPEZ BOTET M.
Expression and function of NKG2D in CD4+ T cells specific for human cytomegalovirus.
Eur. J. Immunol. 36:3198/3206, 2006
PubMed Abstract
SANTORO A.-CANNELLA S.-BOSSI G.-GALLO F.-TRIZZINO A.-PENDE D.-DIELI F.-BRUNO G.-STINCHCOMBE J.-MICALIZZI C.-DE FUSCO C.-DANESINO C.-MORETTA L.-NOTARANGELO L.-GRIFFITHS G.-ARICO' M.
Novel Munc13/4 mutations in children and young adult patients with haemophagocytic lymphohistiocytosis.
J. Med. Genet. 43:953/960, 2006
PubMed Abstract
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