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Regolazione dell'espressione genica

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 punto elenco Presentazione della struttura
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 punto elenco Ricerche 2010-2011
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BRIATA P.-CHEN C.-GIOVARELLI M.-PASERO M.-TRABUCCHI M.-RAMOS A.- GHERZI R.
KSRP, many functions for a single protein.
Front. Biosci. 16:1787/1796, 2011
PubMed Abstract

LIN W.-ZHENG X.-LIN C.-TSAO J.-ZHU X.-CODY J.-COLEMAN J.-GHERZI R.- LUO M.-TOWNES T.-PARKER J.-CHEN C.
Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection.
Mol. Cell. Biol. 31(16):3196/3207, 2011
PubMed Abstract



DIAZ MORENO I.-HOLLINGWORTH D.-KELLY G.-MARTIN S.-GARCIA MAYORAL M.-BRIATA P.-GHERZI R.-RAMOS A.
Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets.
Nucleic Acids Res. 38(15):5193/5205, 2010
PubMed Abstract



DIAZ MORENO I.-HOLLINGWORTH D.-FRENKIEL T.-KELLY G.-MARTIN S.- HOWELL S.-GARCIA MAYORAL M.-GHERZI R.-BRIATA P.-RAMOS A.
Phosphorylation mediated unfolding of a KH domain regulates KSRP localization via 14/3/3 binding.
Nat. Struct. Mol. Biol. 16:238/246, 2009
PubMed Abstract

GHERZI R.-TRABUCCHI M.-PONASSI M.-GALLOUZI I.-ROSENFELD M.-BRIATA P.
Akt2 mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation.
Cell Death Differ. 17:975/983, 2010 - Epub Dec 18, 2009
PubMed Abstract

NECHAMA M.-PENG Y.-BELL O.-BRIATA P.-GHERZI R.-SCHOENBERG D.-NAVEH MANY T.
KSRP/PMR1/exosome association determines parathyroid hormone mRNA levels and stability in transfected cells.
BMC Cell Biol. 10:70;1/70;12, 2009
PubMed Abstract

RUGGIERO T.-TRABUCCHI M.-DE SANTA F.-ZUPO S.-HARFE B.-MCMANUS M.- ROSENFELD M.-BRIATA P.-GHERZI R.
LPS induces KH type splicing regulatory protein dependent processing of microRNA/155 precursors in macrophages.
FASEB J. 23:2898/2908, 2009
PubMed Abstract

TRABUCCHI M.-BRIATA P.-FILIPOWICZ W.-ROSENFELD M.-RAMOS A.-GHERZI R.
How to control miRNA maturation? Co/activators and co/repressors take the stage.
RNA Biol. 6:536/540, 2009
PubMed Abstract

TRABUCCHI M.-BRIATA P.-GARCIA MAYORAL M.-HAASE A.-FILIPOWICZ W.- RAMOS A.-GHERZI R.-ROSENFELD M.
The RNA binding protein KSRP promotes the biogenesis of a subset of microRNAs. Letter.
Nature 459:1010/1014, 2009
PubMed Abstract



NECHAMA M.-BEN DOV I.-BRIATA P.-GHERZI R.-NAVEH MANY T.
The mRNA decay promoting factor K/homology splicing regulator protein post transcriptionally determines parathyroid hormone mRNA levels.
FASEB J. 22:3458/3468, 2008
PubMed Abstract



GARCIA MAYORAL M.-HOLLINGWORTH D.-MASINO L.-DIAZ I.-KELLY G.-GHERZI R.-CHOU C.-CHEN C.-RAMOS A.
The structure of the C terminal KH domains of KSRP reveals a noncanonical motif important for mRNA degradation.
Structure 15:485/498, 2007
PubMed Abstract

GHERZI R.-TRABUCCHI M.-PONASSI M.-RUGGIERO T.-CORTE G.-MORONI C.-CHEN C.-KHABAR K.-ANDERSEN J.-BRIATA P.
The RNA binding protein KSRP promotes decay of beta/catenin mRNA and is inactivated by PI3K/AKT signaling.
PLoS Biol. 5:82/95, 2007
PubMed Abstract

RUGGIERO T.-TRABUCCHI M.-PONASSI M.-CORTE G.-CHEN C.-AL HAJ L.-KHABAR K.-BRIATA P.-GHERZI R.
Identification of a set of KSRP target transcripts upregulated by PI3K/AKT signaling.
BMC Mol. Biol. 8:28;1/28;15, 2007
PubMed Abstract



BEVILACQUA A.-GHISOLFI L.-FRANZI S.-MARESCA G.-GHERZI R.-CAPACCIOLI S.-NICOLIN A.-CANTI G.
Stabilization of cellular mRNAs and upregulation of proteins by oligoribonucleotides homologous to the Bcl2 ARE motif.
Mol. Pharmacol. 71:531/538, 2007 - Epub Oct 31, 2006
PubMed Abstract

CHOU C.-MULKY A.-MAITRA S.-LIN W.-GHERZI R.-KAPPES J.-CHEN C.
Tethering KSRP, a decay promoting AU rich element binding protein, to mRNAs elicits mRNA decay.
Mol. Cell. Biol. 26:3695/3706, 2006
PubMed Abstract

Per le pubblicazioni 2000-2005 del personale della struttura vedere gli elenchi generali.



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